Rigor and Reproducibility in Genetics and Genomics
  • Author : Anonim
  • Release Date : 01 July 2021
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 472
  • ISBN 13 : 9780128172193

Download or read book entitled Rigor and Reproducibility in Genetics and Genomics written by Anonim and published by Academic Press online. This book was released on 01 July 2021 with total pages 472. Available in PDF, EPUB and Kindle. Book excerpt: Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists. Provides practical approaches and step-by-step protocols to strengthen genetic and genomic research conducted in the lab or classroom Through illustrative case studies and training exercises, discusses common pitfalls and solutions for genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing, among other genetic and genomic approaches Specifically examines best practices for microarray analysis, DNA-seq, RNA-seq, gene expression validation, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis

Issues in Returning Individual Results from Genome Research Using Population Based Banked Specimens  with a Focus on the National Health and Nutrition Examination Survey

Issues in Returning Individual Results from Genome Research Using Population Based Banked Specimens with a Focus on the National Health and Nutrition Examination Survey

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on National Statistics,Steering Committee for the Workshop on Guidelines for Returning Individual Results from Genome Research Using Population-Based Banked Specimens
Publisher : National Academies Press
Genre : Social Science
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