Toxicogenomics-Based Cellular Models
  • Author : Jos Kleinjans
  • Release Date : 29 January 2014
  • Publisher : Unknown
  • Genre : Medical
  • Pages : 362
  • ISBN 13 : 0123978629

Download or read book entitled Toxicogenomics-Based Cellular Models written by Jos Kleinjans and published by Unknown online. This book was released on 29 January 2014 with total pages 362. Available in PDF, EPUB and Kindle. Book excerpt: Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores 'omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing. Describes the state-of-the-art in developing toxicogenomics-based cellular models for chemical-induced carcinogenicity, immunotoxicity, developmental toxicity, neurotoxicity and reproduction toxicity Illustrates how to validate toxicogenomics-based alternative test models and provides an outlook to societal and economic implementation of these novel assays Includes an overview of current testing methods and risk assessment frameworks Provides a real-world assessment by articulating the current development and challenges in toxicogenomics while suggesting ways to move this field forward

Toxicogenomics

Toxicogenomics

Author : Tohru Inoue,William T. Pennie
Publisher : Springer Science & Business Media
Genre : Medical
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