Transporters in Drug Discovery and Development
  • Author : Yurong Lai
  • Release Date : 22 August 2014
  • Publisher : Woodhead Publishing
  • Genre : Medical
  • Pages : 780
  • ISBN 13 : 9781908818287

Download or read book entitled Transporters in Drug Discovery and Development written by Yurong Lai and published by Woodhead Publishing online. This book was released on 22 August 2014 with total pages 780. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments. A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development Balanced coverage of molecular biology aspects and functional outcomes State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity